Journal of Medicinal Chemistry
Volume 41, Issue 24 (November 19, 1998)
Copyright © 1998
American Chemical Society
COMMUNICATIONS TO THE EDITOR | |
4677-4680 | Novel CDC25A Phosphatase Inhibitors from Pyrolysis of 3--Azido-B-homo-6-oxa-4-cholesten-7-one on Silica Gel
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EXPEDITED ARTICLES | |
4681-4685 | Syntheses of New Isodethiaazacephems as Potent Antibacterial Agents
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ARTICLES | |
4686-4692 | Synthesis and Evaluation of 11-Substituted 21-Chloro/Iodo-(17,20E/Z)-19-norpregna-1,3,5(10),20-tetraene-3,17-diols: High-Affinity Ligands for the Estrogen Receptor
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4693-4705 | Nonpeptide Somatostatin Agonists with sst4 Selectivity: Synthesis and Structure-Activity Relationships of Thioureas
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4706-4715 | Synthesis, Activity, and Molecular Modeling of New 2,4-Dioxo-5-(naphthylmethylene)-3-thiazolidineacetic Acids and 2-Thioxo Analogues as Potent Aldose Reductase Inhibitors
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4716-4722 | Synthesis and Cytotoxicity of 2-Methyl-4,9-dihydro-1-substituted-1H-imidazo[4,5-g]quinoxaline-4,9-diones and 2,3-Disubstituted-5,10-pyrazino[2,3-g]quinoxalinediones
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4723-4732 | Conformationally Restricted Analogues of 1N,12N-Bisethylspermine: Synthesis and Growth Inhibitory Effects on Human Tumor Cell Lines
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4733-4743 | Synthesis of 7-Benzylamino-6-chloro-2-piperazino-4-pyrrolidinopteridine and Novel Derivatives Free of Positional Isomers. Potent Inhibitors of cAMP-Specific Phosphodiesterase and of Malignant Tumor Cell Growth
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4744-4754 | DNA-Directed Alkylating Agents. 7. Synthesis, DNA Interaction, and Antitumor Activity of Bis(hydroxymethyl)- and Bis(carbamate)-Substituted Pyrrolizines and Imidazoles
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4755-4766 | Indolequinone Antitumor Agents: Correlation between Quinone Structure, Rate of Metabolism by Recombinant Human NAD(P)H:Quinone Oxidoreductase, and in Vitro Cytotoxicity
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4767-4776 | De Novo Design, Synthesis, and Biological Activities of High-Affinity and Selective Non-Peptide Agonists of the -Opioid Receptor
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4777-4789 | Conformational Analysis and Automated Receptor Docking of Selective Arylacetamide-Based -Opioid Agonists
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4790-4799 | Selective Tight Binding Inhibitors of Trypanosomal Glyceraldehyde-3-phosphate Dehydrogenase via Structure-Based Drug Design
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4800-4818 | Covalent Modification of Cyclooxygenase-2 (COX-2) by 2-Acetoxyphenyl Alkyl Sulfides, a New Class of Selective COX-2 Inactivators
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4819-4832 | Antileishmanial Chalcones: Statistical Design, Synthesis, and Three-Dimensional Quantitative Structure-Activity Relationship Analysis
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4833-4843 | Design and Synthesis of Hydrazinopeptides and Their Evaluation as Human Leukocyte Elastase Inhibitors
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4844-4853 | Design, Synthesis, and Biological Activity of Prazosin-Related Antagonists. Role of the Piperazine and Furan Units of Prazosin on the Selectivity for 1-Adrenoreceptor Subtypes
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4854-4860 | 1,2-Benzisothiazol-3-one 1,1-Dioxide Inhibitors of Human Mast Cell Tryptase
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4861-4872 | Exploration of Biologically Relevant Conformations of Anandamide, 2-Arachidonylglycerol, and Their Analogues Using Conformational Memories
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4873-4884 | Human Telomerase Inhibition by Regioisomeric Disubstituted Amidoanthracene-9,10-diones
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4885-4889 | Synthesis and Biological Evaluation of 4-Chloro-3,5-dinitrobenzotrifluoride Analogues as Antileishmanial Agents
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4890-4902 | (+)-4-[2-[4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]- pyridin-11(R)-yl)-1-piperidinyl]-2-oxo-ethyl]-1-piperidinecarboxamide (SCH-66336): A Very Potent Farnesyl Protein Transferase Inhibitor as a Novel Antitumor Agent
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NOTES | |
4903-4909 | N-[2-[4-(4-Chlorophenyl)piperazin-1-yl]ethyl]-3-methoxybenzamide: A Potent and Selective Dopamine D4 Ligand
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ADDITIONS AND CORRECTIONS | |
4910-4910 |
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